Steroids and derivatives
Apexbio Technology LLC Hydrocortisone(Synonyms: Cortisol, 17-Hydroxycorticosterone, Kendall's Compound F), 1g, CAS: 50-23-7.
Hydrocortisone (CAS 50-23-7) is an endogenous glucocorticoid primarily synthesized and secreted by the adrenal cortex It exerts biological effects by binding glucocorticoid receptors altering gene expression involved in metabolic regulation immune response modulation and anti-inflammatory pathways Widely utilized in biomedical research hydrocortisone serves as a standard reference agent for investigating glucocorticoid receptor signaling inflammation models and stress response mechanisms
Sigma Aldrich Fine Chemicals Biosciences Escin | Purity: 98% | Mol Wt: 1131.19 | CAS No: 6805-41-0 | MDL No: MFCD00130460 | 500mg
Escin | Purity: 98% | Mol Wt: 1131.19 | CAS No: 6805-41-0 | MDL No: MFCD00130460 | 500mg
Cayman Chemical Dexamethasone Phosphate sodi
A glucocorticoid; reduces LPS-induced production of RANTES, TGF-β1, and NO in BV-2 microglia from 1-4 µM; reverses LPS-induced decreases in IL-10 levels in, and inhibits LPS-induced migration of, BV-2 microglia at 4 µM; decreases motor activity and reduces adrenal weight and plasma corticosterone levels in rats when administered in the drinking water at 5 UG/ml; reduces joint swelling in a rat model of collagen-induced arthritis at 1.6 mg/kg per day for a minimum of seven days; reduces pruritis and the clinical lesion score in cats with hypersensitivity dermatitis
Cayman Chemical Dexamethasone Phosphate sodi
A glucocorticoid; reduces LPS-induced production of RANTES, TGF-β1, and NO in BV-2 microglia from 1-4 µM; reverses LPS-induced decreases in IL-10 levels in, and inhibits LPS-induced migration of, BV-2 microglia at 4 µM; decreases motor activity and reduces adrenal weight and plasma corticosterone levels in rats when administered in the drinking water at 5 UG/ml; reduces joint swelling in a rat model of collagen-induced arthritis at 1.6 mg/kg per day for a minimum of seven days; reduces pruritis and the clinical lesion score in cats with hypersensitivity dermatitis
Medchemexpress LLC Dopamine D2 receptor agonist-3 | 1257326-24-1 | 98.3% | 295.81 | C15H22ClN3O | 5 MG
Dopamine D2 receptor agonist-3 is a small-molecule research compound that acts as a selective dopamine D2 receptor partial agonist and a dopamine D3 receptor antagonist, with reported in vitro potency and demonstrated brain penetration in vivo. It is supplied as a solid (white to off-white) with high stated purity for laboratory use.
- Selective D2 partial agonist and D3 antagonist activity.
- Potency reported as pEC50 D2 = 8.3; D3 < 5.5 (approx. D2 EC50 ≈ 5 nM).
- Demonstrated brain penetration (brain:blood ratio 5.5; Tmax 0.5 h at 3 mg/kg, s.c.).
- High purity (98.3%) suitable for research applications.
- Solid, white to off-white appearance, available in small research pack sizes.